Description

1-Nitro-4-(2,2,2-Trifluoro-1-Methyl-Ethyl)Benzene is a specialized aromatic nitro compound featuring a trifluoromethyl-substituted isopropyl group, making it a valuable fluorinated building block. This compound matters for its role in introducing both nitro and trifluoromethyl functionalities, which are critical for modulating the electronic properties, lipophilicity, and metabolic stability of target molecules. It is primarily needed by researchers and manufacturers in the pharmaceutical and agrochemical industries for the synthesis of advanced intermediates in drug discovery and crop protection agents.

Application

• Pharmaceutical Intermediate: A key fluorinated synthon for the research and development of active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Precursor: Serves as a starting material for synthesizing specialty polymers, liquid crystals, and organic electronic materials requiring specific fluorine content.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new reactions and creating libraries of fluorinated compounds for screening.
• Dye and Pigment Intermediate: Can be utilized in the synthesis of specialized dyes and pigments where the nitro and fluorine groups alter color properties and fastness.

Basic Information

Product Name	1-Nitro-4-(2,2,2-Trifluoro-1-Methyl-Ethyl)Benzene
CAS No.	1221272-94-1
Molecular Formula	C9H8F3NO2
Molecular Weight	219.16 g/mol
Synonyms	4-(1,1,1-Trifluoropropan-2-yl)nitrobenzene; 1-Nitro-4-(1,1,1-trifluoro-2-propyl)benzene; α,α,α-Trifluoro-2-(4-nitrophenyl)propane; 2-(4-Nitrophenyl)-1,1,1-trifluoropropane; p-Nitro-α,α,α-trifluorocumene; 4-Nitro-α,α,α-trifluoroisopropylbenzene; (2,2,2-Trifluoro-1-methyl-ethyl)-4-nitro-benzene
EINECS	Contact for details

Quality Control

Our 1-Nitro-4-(2,2,2-Trifluoro-1-Methyl-Ethyl)Benzene is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request. We adhere to cGMP standards where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its light-sensitive nature and potential for oxidation, it is recommended to store under an inert atmosphere for long-term preservation. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.