Description

tert-Butyl (3-Fluorocyclopentyl)Carbamate is a high-purity, fluorinated carbamate derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its role in introducing the 3-fluorocyclopentyl moiety, a structural motif of significant interest in medicinal chemistry for modulating the pharmacokinetic and binding properties of target molecules. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated fluorine chemistry.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, especially in CNS and oncology therapeutic areas.
• Medicinal Chemistry: Used for structure-activity relationship (SAR) studies to explore the effects of fluorination on cyclopentyl rings within lead compounds.
• Proteolysis Targeting Chimera (PROTAC) Synthesis: Serves as a component for constructing linkers or ligands in bifunctional degrader molecules.
• Peptidomimetic Research: Incorporated into peptide backbones to enhance metabolic stability and membrane permeability.
• Agrochemical Development: Potential intermediate in the synthesis of advanced, fluorinated pesticides or herbicides.
• Material Science: Exploration as a monomer or precursor for specialized fluorinated polymers with unique properties.

Basic Information

Product Name	tert-Butyl (3-Fluorocyclopentyl)Carbamate
CAS No.	1215071-14-9
Molecular Formula	C10H18FNO2
Molecular Weight	203.26 g/mol
Synonyms	Boc-3-Fluorocyclopentylamine; N-Boc-3-Fluorocyclopentanamine; 3-Fluorocyclopentylcarbamic Acid tert-Butyl Ester; tert-Butyl N-(3-Fluorocyclopentyl)carbamate; 1,1-Dimethylethyl N-(3-Fluorocyclopentyl)carbamate; (3-Fluorocyclopentyl)carbamic Acid tert-Butyl Ester; N-(tert-Butoxycarbonyl)-3-fluorocyclopentanamine
EINECS	Contact for details

Quality Control

Our tert-Butyl (3-Fluorocyclopentyl)Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.