Description

3-Azabicyclo[3.1.0]Hexane, 6,6-Difluoro-, Hydrochloride is a high-value, bicyclic amine hydrochloride salt featuring a unique strained ring system and fluorine substitution. This compound serves as a critical pharmaceutical intermediate and advanced building block in modern organic synthesis, enabling the development of novel bioactive molecules. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug discovery programs.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its unique fluorine-containing bicyclic scaffold.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Biology Probe Synthesis: Employed in the creation of molecular probes for studying enzyme function and biological pathways.
• Material Science: Potential monomer or additive for advanced polymers and functional materials requiring specific rigidity and fluorine content.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthetic routes.

Basic Information

Product Name	3-Azabicyclo[3.1.0]Hexane, 6,6-Difluoro-, Hydrochloride
CAS No.	1215071-13-8
Molecular Formula	C5H8ClF2N
Molecular Weight	155.57 g/mol
Synonyms	6,6-Difluoro-3-azabicyclo[3.1.0]hexane hydrochloride; 3-Azabicyclo[3.1.0]hexane, 6,6-difluoro-, hydrochloride (1:1); 6,6-Difluoro-3-azabicyclo[3.1.0]hexane HCl; 6,6-Difluoro-3-azabicyclo[3.1.0]hexane hydrochloride salt; Difluorinated 3-azabicyclo[3.1.0]hexane HCl; 3-Aza-6,6-difluorobicyclo[3.1.0]hexane hydrochloride
EINECS	Contact for details

Quality Control

Our 3-Azabicyclo[3.1.0]Hexane, 6,6-Difluoro-, Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and MS, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are available upon request for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator to prevent degradation upon exposure to air.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.