Description

Benzonitrile, 2-Methyl-6-(Trifluoromethyl)- is a high-value, multi-functional aromatic nitrile building block distinguished by its trifluoromethyl and methyl substituents. This compound is critical for introducing lipophilicity and metabolic stability into target molecules, making it a sought-after intermediate in advanced chemical synthesis. It is primarily required by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of specialty chemicals for electronic applications, including liquid crystal displays and organic light-emitting diodes.
• Functional Material Development: Employed in polymer chemistry and material science to create polymers with specific thermal, optical, or surface properties.
• Cross-Coupling Reactions: Acts as a versatile substrate in palladium-catalyzed reactions (e.g., Suzuki, Sonogashira) for constructing complex biaryl systems in discovery chemistry.
• Chemical Research & Development: Utilized in academic and industrial R&D labs as a standard or novel reagent for exploring new synthetic methodologies and reaction pathways.

Basic Information

Product Name	Benzonitrile, 2-Methyl-6-(Trifluoromethyl)-
CAS No.	1214385-32-6
Molecular Formula	C9H6F3N
Molecular Weight	185.15 g/mol
Synonyms	2-Methyl-6-(trifluoromethyl)benzonitrile; 6-(Trifluoromethyl)-2-methylbenzonitrile; 2-Methyl-α,α,α-trifluoro-o-tolunitrile; o-Tolunitrile, 2-methyl-6-(trifluoromethyl)-; 2-Cyano-3-methylbenzotrifluoride; 2-Methyl-6-trifluoromethylbenzonitrile; Benzonitrile, 2-methyl-6-(trifluoromethyl)-; 1214385-32-6
EINECS	Contact for details

Quality Control

Our Benzonitrile, 2-Methyl-6-(Trifluoromethyl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0% (Standard Grade)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.