Description

Benzonitrile, 3-Methyl-2-(Trifluoromethyl)- is a high-purity, specialty fluorinated aromatic nitrile building block. This compound is valued for its unique trifluoromethyl-substituted benzonitrile structure, which imparts desirable properties like enhanced lipophilicity and metabolic stability in advanced molecular design. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for constructing drug candidates, particularly in medicinal chemistry programs targeting CNS, oncology, and anti-inflammatory pathways.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group improves bioactivity and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display technologies and organic light-emitting diodes (OLEDs).
• Advanced Polymer Chemistry: Incorporated as a monomer or modifier to create specialty polymers with tailored thermal, chemical, and surface properties.
• Chemical Research & Development: Employed as a versatile building block in academic and industrial R&D for exploring new reactions and creating compound libraries.
• Coordination Chemistry & Ligand Design: The nitrile group can act as a ligand for metal complexes used in catalysis and material science.

Basic Information

Product Name	Benzonitrile, 3-Methyl-2-(Trifluoromethyl)-
CAS No.	1214377-26-0
Molecular Formula	C9H6F3N
Molecular Weight	185.15 g/mol
Synonyms	2-(Trifluoromethyl)-3-methylbenzonitrile; 3-Methyl-2-(trifluoromethyl)benzonitrile; 2-Trifluoromethyl-3-methylbenzonitrile; 3-Methyl-α,α,α-trifluoro-o-tolunitrile; o-Tolunitrile, 3-methyl-2-(trifluoromethyl)-; 1-Cyano-3-methyl-2-(trifluoromethyl)benzene
EINECS	Contact for details

Quality Control

Our Benzonitrile, 3-Methyl-2-(Trifluoromethyl)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including GC, HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.