Description

2-Chloro-1-(Difluoromethyl)-3-(Trifluoromethyl) Benzene is a high-value, multi-fluorinated aromatic building block essential for advanced chemical synthesis. Its unique structure, featuring both chloro and fluoromethyl substituents, makes it a critical intermediate for introducing specific steric and electronic properties into target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used to develop next-generation herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Liquid Crystal & OLED Materials: Serves as a fluorinated core structure in the production of advanced electronic display materials.
• Polymer & Resin Modifier: Imparts unique properties like chemical resistance and thermal stability when incorporated into specialty polymers.
• Organic Synthesis Building Block: Enables complex cross-coupling and functional group transformation reactions in medicinal and process chemistry.
• Research & Development: A vital tool for academic and industrial R&D labs exploring new fluorinated compounds and their properties.

Basic Information

Product Name	2-Chloro-1-(Difluoromethyl)-3-(Trifluoromethyl) Benzene
CAS No.	1214347-72-4
Molecular Formula	C9H4ClF5
Molecular Weight	242.57 g/mol
Synonyms	2-Chloro-α,α-difluoro-3-(trifluoromethyl)benzyl Fluoride; 1-Chloro-2-(difluoromethyl)-4-(trifluoromethyl)benzene; 2-Chloro-1-(difluoromethyl)-3-(trifluoromethyl)benzene; Benzene, 2-chloro-1-(difluoromethyl)-3-(trifluoromethyl)-; 2-Chloro-α,α-difluoro-α,3-bis(trifluoromethyl)toluene (incorrect but common alias); 2-Chloro-α,α-difluoro-3-trifluoromethyltoluene
EINECS	Contact for details

Quality Control

Our production of 2-Chloro-1-(Difluoromethyl)-3-(Trifluoromethyl) Benzene adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and GC-MS and NMR for structural confirmation and impurity profiling. We provide detailed Certificates of Analysis (COA) with each shipment to ensure traceability and compliance with your internal specifications and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reactive metals. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.