Description

1-Fluoro-2-Nitro-3-(Trifluoromethyl)Benzene is a high-value, multi-functional fluorinated aromatic building block. Its unique structure, featuring both electron-withdrawing nitro and trifluoromethyl groups on a fluorinated benzene ring, makes it an essential intermediate for synthesizing complex molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system disorders and oncology.
• Agrochemical Synthesis: Used to develop advanced herbicides, fungicides, and insecticides where the fluorine and trifluoromethyl groups enhance biological activity and environmental stability.
• Material Science Research: Serves as a building block for creating specialty polymers, liquid crystals, and organic electronic materials due to its aromatic and fluorinated properties.
• Dye and Pigment Manufacturing: Intermediate for producing high-performance, light-fast dyes and pigments.
• Cross-Coupling Reactions: Valuable substrate in palladium-catalyzed reactions (e.g., Suzuki, Buchwald-Hartwig) for constructing complex biaryl structures in medicinal chemistry.

Basic Information

Product Name	1-Fluoro-2-Nitro-3-(Trifluoromethyl)Benzene
CAS No.	1214335-98-4
Molecular Formula	C7H3F4NO2
Molecular Weight	209.10 g/mol
Synonyms	2-Nitro-1-fluoro-3-(trifluoromethyl)benzene; 3-(Trifluoromethyl)-2-nitrofluorobenzene; 1-Fluoro-2-nitro-α,α,α-trifluorotoluene; 2-Nitro-α,α,α-trifluoro-m-fluorotoluene; Benzene, 1-fluoro-2-nitro-3-(trifluoromethyl)-; m-(Trifluoromethyl)-o-nitrofluorobenzene
EINECS	Contact for details

Quality Control

Every batch of 1-Fluoro-2-Nitro-3-(Trifluoromethyl)Benzene is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the precise requirements for advanced synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment, and custom specifications can be developed to support your project.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.