Description

2-Fluoro-4-(4-Fluorophenyl)Benzonitrile is a high-value, multi-functional aromatic nitrile building block featuring a biphenyl core with strategic fluorine substitutions. This compound is essential for advanced organic synthesis, offering a versatile scaffold for constructing complex molecules with tailored electronic and steric properties. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, material science, and as a key intermediate in the synthesis of active ingredients.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and inflammatory diseases.
• Agrochemical Synthesis: Serves as a key building block for developing novel herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and metabolic stability.
• Material Science Research: Used in the development of organic electronic materials, such as organic light-emitting diodes (OLEDs) and liquid crystals, due to its conjugated biphenyl structure.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create sophisticated ligands for catalysis, leveraging the nitrile group for metal coordination.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2-Fluoro-4-(4-Fluorophenyl)Benzonitrile
CAS No.	1214332-40-7
Molecular Formula	C13H7F2N
Molecular Weight	215.20 g/mol
Synonyms	4'-Fluoro-2-fluoro[1,1'-biphenyl]-4-carbonitrile; [1,1'-Biphenyl]-4-carbonitrile, 4'-fluoro-2-fluoro-; 2,4'-Difluorobiphenyl-4-carbonitrile; 4-(4-Fluorophenyl)-2-fluorobenzonitrile; 2-Fluoro-4'-fluorobiphenyl-4-carbonitrile
EINECS	Contact for details

Quality Control

Our 2-Fluoro-4-(4-Fluorophenyl)Benzonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications. Our quality commitment supports applications in GMP and ISO-regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.