Description

2-Fluoro-3-Nitrobenzonitrile is a versatile fluorinated aromatic nitrile building block, essential for advanced organic synthesis. Its unique structure, featuring both an electron-withdrawing nitro group and a fluorine atom ortho to the nitrile, makes it a critical intermediate for constructing complex molecules with tailored electronic properties. This compound is primarily utilized by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, leveraging the fluorine atom for enhanced bioactivity and metabolic stability.
• Material Science Research: Serves as a building block for creating specialty polymers, liquid crystals, and organic electronic materials due to its polarizable nitrile group.
• Chemical Biology Probes: Employed in the design of fluorescent tags, enzyme inhibitors, and other molecular probes for diagnostic and research applications.
• Cross-Coupling Reactions: An effective substrate for palladium-catalyzed reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce complex aryl systems.
• Nitrile Transformation Chemistry: The nitrile functional group can be converted into amides, acids, tetrazoles, and heterocycles, expanding its utility in library synthesis.

Basic Information

Product Name	2-Fluoro-3-Nitrobenzonitrile
CAS No.	1214328-20-7
Molecular Formula	C7H3FN2O2
Molecular Weight	166.11 g/mol
Synonyms	3-Nitro-2-fluorobenzonitrile; 2-Fluoro-3-nitrobenzenecarbonitrile; Benzonitrile, 2-fluoro-3-nitro-; 2-Fluoro-3-nitro-phenyl cyanide; 1214328-20-7; FC6H3(NO2)CN
EINECS	Contact for details

Quality Control

Our 2-Fluoro-3-Nitrobenzonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment ensures the material meets the high standards required for research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.