Description

1-(Difluoromethoxy)-2-Fluoro-3-Nitro-Benzene is a high-purity fluorinated aromatic nitro compound, serving as a critical advanced intermediate in modern synthetic chemistry. Its unique difluoromethoxy and fluoro-nitro substitution pattern makes it a valuable building block for introducing specific functionalities into target molecules. This compound is primarily required by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting new therapeutic agents.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for specialty polymers and advanced organic electronic materials due to its electron-withdrawing nitro group and fluorine content.
• Ligand and Catalyst Development: Employed in the creation of novel fluorinated ligands for catalysis and molecular recognition applications.
• Fluorination Chemistry Studies: A valuable substrate for studying new fluorination methodologies and reaction mechanisms in academic and industrial R&D settings.

Basic Information

Product Name	1-(Difluoromethoxy)-2-Fluoro-3-Nitro-Benzene
CAS No.	1214326-24-5
Molecular Formula	C7H4F3NO3
Molecular Weight	207.11 g/mol
Synonyms	2-Fluoro-3-nitro-1-(difluoromethoxy)benzene; 1-(Difluoromethoxy)-2-fluoro-3-nitrobenzene; Benzene, 1-(difluoromethoxy)-2-fluoro-3-nitro-; 2-Fluoro-α,α-difluoro-3-nitroanisole; 3-Nitro-2-fluoro-1-(difluoromethoxy)benzene
EINECS	Contact for details

Quality Control

Our production of 1-(Difluoromethoxy)-2-Fluoro-3-Nitro-Benzene adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. The material is characterized and released against comprehensive specifications, including identity confirmation by spectroscopic methods and purity assessment by chromatographic techniques. A Certificate of Analysis (COA) detailing the specific results for each batch is provided to guarantee it meets the requirements for advanced synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.