Description

(R)-2,2,2-Trifluoro-1-(3-Isopropyl-Phenyl)-Ethylamine is a high-purity chiral amine building block featuring a trifluoromethyl group and an isopropyl-substituted aromatic ring. This compound is valued for its role as a critical intermediate in the synthesis of advanced pharmaceutical agents, particularly where the introduction of fluorine atoms and specific stereochemistry is required to modulate biological activity and metabolic stability. It is primarily sought by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel drug candidates, especially in central nervous system (CNS) and anti-inflammatory therapies.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides where the trifluoromethyl group enhances efficacy and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of fluorinated polymers and advanced organic materials with unique properties.
• Chemical Biology Probes: Utilized in the design of molecular probes for studying enzyme mechanisms and protein interactions.

Basic Information

Product Name	(R)-2,2,2-Trifluoro-1-(3-Isopropyl-Phenyl)-Ethylamine
CAS No.	1213056-35-9
Molecular Formula	C11H14F3N
Molecular Weight	217.23 g/mol
Synonyms	(R)-1-(3-Isopropylphenyl)-2,2,2-trifluoroethanamine; (R)-α-(Trifluoromethyl)-3-isopropylbenzeneethanamine; (R)-2,2,2-Trifluoro-1-(3-isopropylphenyl)ethan-1-amine; (R)-1-[3-(1-Methylethyl)phenyl]-2,2,2-trifluoroethanamine; (R)-3-Isopropyl-α-(trifluoromethyl)benzeneethanamine; (R)-TFMPEA derivative; (R)-Trifluoromethylated Amphetamine Analog
EINECS	Contact for details

Quality Control

Our (R)-2,2,2-Trifluoro-1-(3-Isopropyl-Phenyl)-Ethylamine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess determination, to ensure compliance with exacting standards for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.