Description

3-Fluoro-2-(Methylsulphonyl)Nitrobenzene, 1-Fluoro-2-(Methylsulphonyl)-3-Nitrobenzene CAS NO 1210693-43-8 is a high-purity, multi-functional aromatic building block characterized by its strategically positioned fluorine, nitro, and methylsulfonyl groups. This compound matters for its role as a critical intermediate in advanced organic synthesis, enabling the construction of complex molecules with precise electronic and steric properties. It is primarily needed by R&D and production teams in the pharmaceutical and agrochemical industries for developing new active ingredients, including potential drug candidates and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex heterocycles and active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, where the fluorine atom enhances biological activity and environmental stability.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Dye & Pigment Manufacturing: Acts as an intermediate for synthesizing advanced colorants and fluorescent markers with specific light-absorption properties.
• Cross-Coupling Reactions: The nitro and sulfonyl groups make it a valuable substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) for carbon-carbon and carbon-heteroatom bond formation.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and protein interactions.

Basic Information

Item	Details
Product Name	3-Fluoro-2-(Methylsulphonyl)Nitrobenzene, 1-Fluoro-2-(Methylsulphonyl)-3-Nitrobenzene
CAS No.	1210693-43-8
Molecular Formula	C7H6FNO4S
Molecular Weight	219.19 g/mol
Synonyms	1-Fluoro-2-(methylsulfonyl)-3-nitrobenzene; 3-Fluoro-2-(methylsulfonyl)nitrobenzene; 2-(Methylsulfonyl)-3-nitrofluorobenzene; 3-Nitro-2-(methylsulfonyl)fluorobenzene; 1-Fluoro-3-nitro-2-(methylsulfonyl)benzene; Benzene, 1-fluoro-2-(methylsulfonyl)-3-nitro-; (Methylsulfonyl)-3-nitrofluorobenzene
EINECS	Contact for details

Quality Control

Our 3-Fluoro-2-(Methylsulphonyl)Nitrobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for sensitive R&D and scale-up processes. Certificates of Analysis (COA) with detailed specifications are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light) and should be handled under an inert atmosphere if prolonged exposure is anticipated.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.