Description

1-(3,5-Difluorophenyl)Cyclopropane-1-Carbonitrile is a high-value, fluorinated cyclopropane nitrile building block. This compound is prized for its unique structural motif, which is critical for modulating the physicochemical and metabolic properties of advanced molecules. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, oncology, and inflammatory diseases.
• Agrochemical Synthesis: Serves as a versatile precursor for creating novel herbicides, fungicides, and insecticides with potentially enhanced activity and environmental profiles.
• Material Science Research: Used in the development of specialty polymers and advanced organic materials where the difluorophenyl and cyclopropane groups impart specific electronic or structural properties.
• Ligand and Catalyst Development: Employed in the synthesis of complex chiral ligands or organocatalysts for asymmetric synthesis applications.
• Chemical Biology Probes: Acts as a building block for creating molecular probes to study enzyme function or biological pathways.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs and research organizations for custom synthesis projects requiring this specific fluorinated architecture.

Basic Information

Product Name	1-(3,5-Difluorophenyl)Cyclopropane-1-Carbonitrile
CAS No.	1205642-06-3
Molecular Formula	C10H7F2N
Molecular Weight	179.17 g/mol
Synonyms	1-(3,5-Difluorophenyl)cyclopropanecarbonitrile; 1-(3,5-Difluorophenyl)cyclopropanecarbonitrile; 3,5-Difluoro-α-(cyclopropylidene)benzenecetonitrile; Cyclopropane-1-carbonitrile, 1-(3,5-difluorophenyl)-; 1-(3,5-Difluorophenyl)cyclopropyl cyanide; 3,5-Difluorobenzenecyclopropanecarbonitrile
EINECS	Contact for details

Quality Control

Our 1-(3,5-Difluorophenyl)Cyclopropane-1-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.