Description

5-Bromo-3-Fluoro-2-Nitrobenzenamine is a high-purity, multi-functional aromatic amine building block designed for advanced chemical synthesis. Its unique halogenated nitroaniline structure makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is essential for R&D and production in the pharmaceutical, agrochemical, and specialty chemical industries, where it serves as a precursor for active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors, antiviral agents, and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, leveraging the fluorine and bromine substituents for enhanced bioactivity and environmental stability.
• Material Science Precursor: Serves as a monomer or functionalization agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Manufacturing: Acts as an intermediate for synthesizing complex azo dyes and high-performance pigments, where the nitro and amine groups are pivotal for color development.
• Cross-Coupling Reactions: An excellent substrate for Buchwald-Hartwig amination, Suzuki-Miyaura, and other palladium-catalyzed cross-coupling reactions to create biaryl and complex amine structures.
• Research & Development: A valuable reagent in academic and industrial R&D for exploring new synthetic pathways and creating compound libraries for screening.

Basic Information

Product Name	5-Bromo-3-Fluoro-2-Nitrobenzenamine
CAS No.	1193385-18-0
Molecular Formula	C6H4BrFN2O2
Molecular Weight	235.01 g/mol
Synonyms	2-Amino-4-bromo-6-fluoronitrobenzene; 4-Bromo-2-fluoro-6-nitroaniline; 2-Nitro-5-bromo-3-fluoroaniline; 5-Bromo-3-fluoro-2-nitroaniline; 2-Amino-5-bromo-3-fluoronitrobenzene; 6-Fluoro-4-bromo-2-nitroaniline; Benzenamine, 5-bromo-3-fluoro-2-nitro-; 1193385-18-0
EINECS	Contact for details

Quality Control

Every batch of 5-Bromo-3-Fluoro-2-Nitrobenzenamine is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure consistency and high purity. Our standard quality protocol includes identity confirmation by FT-IR and NMR, purity determination by HPLC, and control of key impurities. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.