Description

1H-Isoindol-1-One, 5,6-Difluoro-2,3-Dihydro- is a high-value fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used to develop novel pesticides and herbicides where the difluoro-substituted isoindolone core imparts desirable biological activity and metabolic stability.
• Material Science: Serves as a building block for advanced polymers and organic electronic materials, leveraging its rigid, fluorinated structure.
• Chemical Synthesis: Employed in medicinal and process chemistry for structure-activity relationship (SAR) studies and scaffold diversification.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development and the exploration of new chemical spaces.

Basic Information

Product Name	1H-Isoindol-1-One, 5,6-Difluoro-2,3-Dihydro-
CAS No.	1192040-50-8
Molecular Formula	C8H5F2NO
Molecular Weight	169.13 g/mol
Synonyms	5,6-Difluoro-2,3-dihydro-1H-isoindol-1-one; 5,6-Difluoro-1-isoindolinone; 5,6-Difluoro-2,3-dihydroisoindol-1-one; 5,6-Difluoro-1H-isoindol-1-one, 2,3-dihydro-; 5,6-Difluoro-1-isoindolin-1-one; Difluoro-isoindolinone; 1192040-50-8; 5,6-Difluoro-isoindolin-1-one
EINECS	Contact for details

Quality Control

Our 1H-Isoindol-1-One, 5,6-Difluoro-2,3-Dihydro- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.