Description

3A-(Difluoromethyl)-3,3A-Dihydrobenzo[D]Pyrrolo[2,1-B]Thiazol-1(2H)-One is a high-value, complex heterocyclic organic compound featuring a fused benzothiazole-pyrrolidone core with a difluoromethyl substituent. This specific molecular architecture makes it a critical advanced pharmaceutical intermediate (API) and a versatile building block in modern synthetic chemistry. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and anti-infectives.
• Agrochemical Research: Used as a sophisticated building block for developing new-generation herbicides, fungicides, and insecticides, leveraging the biological activity of the difluoromethyl and fused heterocyclic groups.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex molecular architectures, enabling exploration of new chemical space in medicinal and materials chemistry.
• Material Science Research: Investigated as a monomer or functional additive for creating specialty polymers and advanced organic materials with unique electronic or optical properties.

Basic Information

Product Name	3A-(Difluoromethyl)-3,3A-Dihydrobenzo[D]Pyrrolo[2,1-B]Thiazol-1(2H)-One
CAS No.	1191927-89-5
Molecular Formula	C12H9F2NOS
Molecular Weight	253.27 g/mol
Synonyms	3a-(Difluoromethyl)-3,3a-dihydro-2H-benzo[d]pyrrolo[2,1-b]thiazol-1-one; 3a-(Difluoromethyl)-2,3-dihydro-1H-pyrrolo[2,1-b]benzothiazol-1-one; Benzo[d]pyrrolo[2,1-b]thiazol-1(2H)-one, 3a-(difluoromethyl)-3,3a-dihydro-; 1191927-89-5; DFMPT Intermediate; Difluoromethyl Benzothiazole Pyrrolidone
EINECS	Contact for details

Quality Control

Our production of 3A-(Difluoromethyl)-3,3A-Dihydrobenzo[D]Pyrrolo[2,1-B]Thiazol-1(2H)-One adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Products undergo rigorous analytical testing, including HPLC, GC, NMR, and MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support cGMP compliance for pharmaceutical applications and can tailor quality documentation to meet specific client and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be sensitive to moisture and prolonged exposure to air; therefore, it is recommended to store under an inert atmosphere for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.