Description

2,6-Dibromo-4-Fluoro-3-Methylbenzonitrile is a high-purity halogenated benzonitrile derivative, serving as a critical advanced pharmaceutical intermediate and agrochemical building block. Its unique substitution pattern makes it a valuable synthon for constructing complex molecules in medicinal chemistry and crop protection research. This compound is essential for R&D and production teams in the pharmaceutical and agrochemical sectors seeking to develop new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and fungicides, leveraging its halogenated aromatic structure.
• Material Science Research: Serves as a precursor for specialty polymers and liquid crystals, where its bromine and fluorine atoms impart specific electronic and physical properties.
• Organic Synthesis: A versatile reagent for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution, enabling complex molecular architecture.
• Chemical Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation in related chemical production.

Basic Information

Product Name	2,6-Dibromo-4-Fluoro-3-Methylbenzonitrile
CAS No.	1188428-64-9
Molecular Formula	C8H4Br2FN
Molecular Weight	291.93 g/mol
Synonyms	4-Fluoro-3-methyl-2,6-dibromobenzonitrile; 2,6-Dibromo-4-fluoro-3-methylbenzonitrile; Benzonitrile, 2,6-dibromo-4-fluoro-3-methyl-; 3-Methyl-2,6-dibromo-4-fluorobenzonitrile
EINECS	Contact for details

Quality Control

Our 2,6-Dibromo-4-Fluoro-3-Methylbenzonitrile is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.