Description

21-Dehydro-16α-Hydroxy Prednisolone is a key synthetic corticosteroid intermediate with significant pharmacological relevance. This compound is valued for its role in the research and development of novel anti-inflammatory and immunosuppressive agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in advanced steroid synthesis.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of novel corticosteroid drugs and prodrugs.
• Research & Development: Used in biochemical research to study glucocorticoid receptor activity and metabolic pathways.
• Reference Standard: Serves as a high-purity analytical standard for quality control in steroid manufacturing.
• Process Chemistry: Employed in the development and scale-up of advanced steroid synthesis routes.
• Metabolite Studies: Investigated as a potential metabolite or derivative of prednisolone and related steroids.

Basic Information

Product Name	21-Dehydro-16α-Hydroxy Prednisolone
CAS No.	1188271-73-9
Molecular Formula	C21H26O6
Molecular Weight	374.43 g/mol
Synonyms	16α-Hydroxy-21-dehydroprednisolone; (11β)-11,17,21-Trihydroxy-16-methylpregna-1,4-diene-3,20-dione; 16α-Hydroxyprednisolone 21-aldehyde; 21-Dehydro-16α-hydroxyprednisolone; 16α-Methyl-11β,17α,21-trihydroxypregna-1,4-diene-3,20-dione
EINECS	Contact for details

Quality Control

Our 21-Dehydro-16α-Hydroxy Prednisolone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical intermediate applications. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure containers are sealed tightly after each use to minimize exposure to atmospheric moisture and light.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.