Description

21-Dehydro Desoxymetasone is a high-purity synthetic steroid derivative, identified by CAS number 1188271-71-7. This compound serves as a critical advanced intermediate in the research and development of novel pharmaceutical agents, particularly within the field of corticosteroids. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers engaged in the synthesis of complex steroid-based therapeutics.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of novel corticosteroid drug candidates and their analogs.
• Biochemical Research: Used as a reference standard or starting material in studies investigating steroid metabolism, receptor binding, and structure-activity relationships (SAR).
• Process Development: Employed in the optimization and scale-up of synthetic routes for steroid-based active pharmaceutical ingredients (APIs).
• Academic Synthesis: Serves as a sophisticated substrate for advanced organic chemistry research and methodology development in steroid chemistry.
• Analytical Standard: Utilized for method development and calibration in analytical techniques such as HPLC and LC-MS for quality control in steroid manufacturing.

Basic Information

Product Name	21-Dehydro Desoxymetasone
CAS No.	1188271-71-7
Molecular Formula	C₂₂H₂₉FO₄
Molecular Weight	376.46 g/mol
Synonyms	21-Dehydrodesoxymetasone; 9α-Fluoro-11β,17α,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione; 21-Dehydro Desoxymethasone; 16α-Methyl-9α-fluoro-11β,17α,21-trihydroxypregna-1,4-diene-3,20-dione; 21-Dehydrodexamethasone Impurity; Desoxymetasone Impurity; 21-Dehydro Derivative of Desoxymetasone
EINECS	Contact for details

Quality Control

Our 21-Dehydro Desoxymetasone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical research intermediates. Certificates of Analysis (COA) detailing purity by HPLC, related substances, and other critical parameters are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.