Description

2-(2-Aminoethyl)-3-Fluorobenzonitrile Hydrochloride is a high-purity, advanced pharmaceutical intermediate and versatile organic building block. This compound is valued for its bifunctional molecular structure, featuring both a primary amine and a nitrile group, which enables its use in complex synthetic pathways. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of novel herbicides and pesticides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a building block for creating chelating ligands and organocatalysts used in asymmetric synthesis.
• Peptidomimetics and Bio-conjugation: The aminoethyl side chain facilitates incorporation into peptide analogs or for creating linker molecules in bioconjugation chemistry.
• Material Science Research: Employed in the synthesis of specialty polymers and functionalized surfaces where fluorinated aromatic groups are desired.
• Chemical Biology Probes: Used to develop fluorescent or affinity probes for studying enzyme mechanisms and protein interactions.

Basic Information

Product Name	2-(2-Aminoethyl)-3-Fluorobenzonitrile Hydrochloride
CAS No.	1188263-91-3
Molecular Formula	C9H10FN2 • HCl
Molecular Weight	200.65 (Free base) / 237.11 (Hydrochloride salt)
Synonyms	3-Fluoro-2-(2-aminoethyl)benzonitrile hydrochloride; 2-(2-Aminoethyl)-3-fluorobenzonitrile HCl; 2-(2-Aminoethyl)-3-fluorobenzonitrile monohydrochloride; 3-Fluoro-2-(2-aminoethyl)benzonitrile monohydrochloride; 2-(2-Aminoethyl)-3-fluorophenyl cyanide hydrochloride; Benzonitrile, 2-(2-aminoethyl)-3-fluoro-, hydrochloride (1:1); 1188263-91-3
EINECS	Contact for details

Quality Control

Our 2-(2-Aminoethyl)-3-Fluorobenzonitrile Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) that include data from HPLC, NMR, and mass spectrometry. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.