Description

5,6-Difluoro-2(3H)-Benzothiazolone is a high-purity fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound is valued for its role as a key intermediate in the development of novel pharmaceuticals and agrochemicals, where the introduction of fluorine atoms can dramatically alter biological activity and metabolic stability. It is primarily sought by research institutions and industrial R&D departments focused on medicinal chemistry, particularly in the synthesis of potential drug candidates and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially in drug discovery programs targeting central nervous system (CNS) disorders, oncology, and anti-infective agents.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and pesticides, where the difluoro-benzothiazolone scaffold can contribute to enhanced efficacy and environmental profile.
• Material Science: Serves as a precursor for the synthesis of advanced organic electronic materials, including dyes, pigments, and ligands for metal-organic frameworks (MOFs).
• Biochemical Tool Compound: Employed in life science research as a probe or inhibitor to study specific enzymatic pathways and biological mechanisms.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in custom synthesis projects and scale-up processes under cGMP conditions.

Basic Information

Product Name	5,6-Difluoro-2(3H)-Benzothiazolone
CAS No.	1188090-34-7
Molecular Formula	C7H3F2NOS
Molecular Weight	187.17 g/mol
Synonyms	5,6-Difluoro-1,3-benzothiazol-2(3H)-one; 5,6-Difluoro-2-hydroxybenzothiazole; 5,6-Difluoro-2-benzothiazolinone; 2(3H)-Benzothiazolone, 5,6-difluoro-; 5,6-Difluoro-2-oxo-2,3-dihydrobenzo[d]thiazole; 5,6-Difluorobenzothiazol-2-one; 5,6-Difluoro-3H-benzo[d]thiazol-2-one
EINECS	Contact for details

Quality Control

Our 5,6-Difluoro-2(3H)-Benzothiazolone is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as identity, assay, and impurity profiles. While produced to meet general reagent-grade standards, material can be supplied under more stringent specifications for advanced applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.