Description

1-Bromo-5-Iodo-4-Nitro-2-(Trifluoromethoxy)Benzene is a high-value, multi-functional halogenated aromatic building block. This compound is engineered for advanced organic synthesis, offering a unique combination of reactive halogen sites and electron-withdrawing groups for precise molecular construction. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting complex heterocycles and fluorinated molecules.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Material Science: Serves as a monomer or functionalization agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions (e.g., Suzuki, Sonogashira, Buchwald-Hartwig) due to the presence of both bromo and iodo substituents, allowing for sequential functionalization.
• Chemical Synthesis Building Block: Provides a versatile scaffold for introducing nitro, trifluoromethoxy, and halogen functionalities into more complex molecular architectures.
• R&D and Process Scale-up: Supplied for laboratory-scale research, optimization, and subsequent pilot or commercial-scale manufacturing processes.

Basic Information

Product Name	1-Bromo-5-Iodo-4-Nitro-2-(Trifluoromethoxy)Benzene
CAS No.	1187386-19-1
Molecular Formula	C7H2BrF3INO3
Molecular Weight	421.91 g/mol
Synonyms	2-Bromo-4-Iodo-5-Nitro-1-(Trifluoromethoxy)Benzene; 4-Bromo-2-Iodo-1-Nitro-5-(Trifluoromethoxy)Benzene; Benzene, 1-bromo-5-iodo-4-nitro-2-(trifluoromethoxy)-; 1-Bromo-5-iodo-4-nitro-2-(trifluoromethoxy)benzene
EINECS	Contact for details

Quality Control

Our 1-Bromo-5-Iodo-4-Nitro-2-(Trifluoromethoxy)Benzene is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.