Description

Antihistamine-1 CAS NO 1186430-60-3 is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of next-generation antihistamine compounds. This product is critical for ensuring the efficacy and safety of active pharmaceutical ingredients (APIs) targeting allergic and inflammatory conditions. It is primarily utilized by pharmaceutical R&D departments and contract manufacturing organizations (CMOs) engaged in the development and production of novel therapeutic agents.

Application

• Key intermediate in the synthesis of novel histamine H1-receptor antagonist APIs.
• Research and development of new chemical entities (NCEs) for allergy and asthma medications.
• Precursor in the manufacture of non-sedating antihistamine drugs.
• Building block for pharmaceutical fine chemicals and advanced intermediates.
• Used in academic and industrial research exploring histamine receptor modulation.
• Potential applications in developing treatments for dermatological conditions like urticaria.

Basic Information

Item	Detail
Product Name	Antihistamine-1
CAS No.	1186430-60-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	1-(4-Fluorophenyl)-2-((1-methylpiperidin-4-yl)amino)ethanone; Antihistamine Intermediate-1; H1 Antagonist Intermediate; 4-Fluorophenacyl-1-methyl-4-aminopiperidine; FMPA Intermediate; CAS 1186430-60-3; Lead Compound for Antiallergic Agents
EINECS	Contact for details

Quality Control

Our Antihistamine-1 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets the high-purity standards required for pharmaceutical applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.