Description

2,4-Difluoro-3-Nitrobenzonitrile is a high-purity fluorinated aromatic nitrile building block, identified by CAS NO 1186194-75-1. This compound is valued for its unique molecular architecture, which combines electron-withdrawing nitro and nitrile groups with fluorine substituents, making it a versatile intermediate in advanced synthesis. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for constructing complex molecules, particularly in the development of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel active pharmaceutical ingredients (APIs), especially in fluorinated drug candidates targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and pesticides, where the difluoro-nitrobenzonitrile moiety can enhance biological activity and environmental stability.
• Material Science Precursor: Serves as a building block for advanced organic materials, including liquid crystals, polymers, and organic semiconductors, due to its electron-deficient aromatic core.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution reactions to introduce complex functionalities.
• Dye and Pigment Intermediate: Acts as a precursor in the synthesis of specialized dyes and pigments where fluorine atoms improve lightfastness and color properties.

Basic Information

Product Name	2,4-Difluoro-3-Nitrobenzonitrile
CAS No.	1186194-75-1
Molecular Formula	C7H2F2N2O2
Molecular Weight	184.10 g/mol
Synonyms	3-Nitro-2,4-difluorobenzonitrile; 2,4-Difluoro-3-nitrobenzenecarbonitrile; Benzonitrile, 2,4-difluoro-3-nitro-; 1186194-75-1; 2,4-Difluoro-3-nitro-benzonitrile
EINECS	Contact for details

Quality Control

Every batch of 2,4-Difluoro-3-Nitrobenzonitrile is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation of quality.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.