Description

Betamethasone Tripropionate is a potent synthetic corticosteroid ester derivative, valued for its enhanced lipophilicity and prolonged anti-inflammatory activity. This advanced intermediate is critical for the development of high-potency topical and injectable pharmaceutical formulations. It is primarily utilized by research institutions and pharmaceutical manufacturers specializing in dermatology, rheumatology, and advanced steroid therapies.

Application

• Active Pharmaceutical Ingredient (API) Intermediate: A key synthetic precursor in the manufacture of high-potency corticosteroid drugs.
• Topical Corticosteroid Formulations: Used in the development of creams, ointments, and lotions for treating severe inflammatory skin conditions like psoriasis, eczema, and dermatitis.
• Injectable Steroid Preparations: Serves as a critical component in formulating long-acting intramuscular or intra-articular injections for managing chronic inflammation and autoimmune disorders.
• Pharmaceutical Research & Development: Employed in preclinical and clinical studies to investigate new delivery systems and therapeutic applications of corticosteroids.
• Veterinary Medicine: Used in developing anti-inflammatory treatments for animals.
• Reference Standard: Serves as a high-purity analytical standard for quality control and regulatory testing in pharmaceutical laboratories.

Basic Information

Product Name	Betamethasone Tripropionate
CAS No.	1186048-33-8
Molecular Formula	C30H41FO7
Molecular Weight	532.65 g/mol
Synonyms	9-Fluoro-11β,17,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione 17,21-dipropionate; Betamethasone 17,21-Dipropionate; 16β-Methyl-9α-fluoro-1,4-pregnadiene-11β,17α,21-triol-3,20-dione 17,21-dipropionate; Betamethasone Dipropionate Related Compound C (Propionate Ester); Betamethasone 17-propionate 21-propionate
EINECS	Contact for details

Quality Control

Our Betamethasone Tripropionate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identification by IR and NMR spectroscopy, and residual solvent analysis, to ensure it meets exacting standards for pharmaceutical development. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.