Description

4,6-Difluoro-1-Methyl-1H-Indazole is a high-purity fluorinated indazole derivative, a critical building block in modern synthetic chemistry. Its value lies in its unique molecular scaffold, which is essential for constructing complex molecules with targeted biological activity. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for applications in drug discovery and advanced material synthesis.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and oncology research programs.
• Agrochemical Research: Used in the synthesis of advanced crop protection agents and herbicides, leveraging the biological activity of the difluorinated indazole core.
• Material Science: Serves as a precursor for specialty chemicals and functional materials, including liquid crystals and organic electronic components.
• Chemical Synthesis: An essential fluorinated building block for medicinal chemistry, enabling structure-activity relationship (SAR) studies and lead optimization.
• Academic & Contract Research: Utilized in university and CRO (Contract Research Organization) laboratories for exploratory chemistry and method development.

Basic Information

Product Name	4,6-Difluoro-1-Methyl-1H-Indazole
CAS No.	1185767-08-1
Molecular Formula	C8H6F2N2
Molecular Weight	168.14 g/mol
Synonyms	1-Methyl-4,6-difluoro-1H-indazole; 4,6-Difluoro-1-methylindazole; 1H-Indazole, 4,6-difluoro-1-methyl-; 1185767-08-1; 4,6-Difluoro-1-methyl-1H-indazole; 1-Methyl-4,6-difluoroindazole
EINECS	Contact for details

Quality Control

Our 4,6-Difluoro-1-Methyl-1H-Indazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency suitable for research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. The product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.