Description

3'-Chloro-5'-(Pentafluorosulfur)Acetophenone is a high-value, multi-functional organic intermediate characterized by its unique combination of chloro and pentafluorosulfanyl (SF5) substituents. This compound matters for its role in facilitating the synthesis of complex molecules, particularly in advanced pharmaceutical and agrochemical research where the SF5 group is prized for its metabolic stability and lipophilicity. It is primarily needed by R&D chemists and process development scientists in the life sciences sector for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in medicinal chemistry programs targeting CNS disorders and inflammatory diseases.
• Agrochemical Research: Used in developing next-generation herbicides, fungicides, and insecticides, where the SF5 group enhances biological activity and environmental persistence.
• Material Science: Serves as a precursor for advanced polymers and liquid crystals with unique electronic and thermal properties.
• Chemical Synthesis: A versatile reagent for introducing both chloro and pentafluorosulfanyl functional groups into complex molecular architectures.
• Academic & Industrial R&D: Employed in exploratory chemistry to study structure-activity relationships (SAR) and develop new synthetic methodologies.

Basic Information

Item	Details
Product Name	3'-Chloro-5'-(Pentafluorosulfur)Acetophenone
CAS No.	1180486-96-7
Molecular Formula	C8H4ClF5OS
Molecular Weight	278.63 g/mol
Synonyms	1-(3-Chloro-5-(pentafluoro-λ6-sulfanyl)phenyl)ethan-1-one; 3-Chloro-5-(pentafluorosulfanyl)acetophenone; 3-Chloro-5-SF5-acetophenone; 3'-Chloro-5'-SF5-acetophenone; 1-Acetyl-3-chloro-5-pentafluorosulfanylbenzene; 3-Chloro-5-(pentafluorosulfur)acetophenone; 3-Chloro-5-(SF5)acetophenone
EINECS	Contact for details

Quality Control

Our production of 3'-Chloro-5'-(Pentafluorosulfur)Acetophenone adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical characterization, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our commitment to cGMP principles and compliance with REACH regulations ensures a reliable supply for global research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.