Description

Benzonitrile, 4-(4-Chloro-1H-Pyrazol-1-Yl)-3-Fluoro- is a high-value, fluorinated aromatic nitrile derivative that serves as a critical building block in advanced organic synthesis. Its molecular architecture, featuring a chloropyrazole and a fluorine substituent, makes it an essential intermediate for developing novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex heterocyclic systems.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Building block for developing next-generation herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science Research: Used in the development of advanced organic electronic materials and liquid crystals.
• Chemical Biology Probes: Serves as a scaffold for creating fluorescent tags and molecular probes for biological imaging and diagnostics.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Item	Details
Product Name	Benzonitrile, 4-(4-Chloro-1H-Pyrazol-1-Yl)-3-Fluoro-
CAS No.	1178197-57-3
Molecular Formula	C10H5ClFN3
Molecular Weight	221.62 g/mol
Synonyms	3-Fluoro-4-(4-chloro-1H-pyrazol-1-yl)benzonitrile; 4-(4-Chloro-1H-pyrazol-1-yl)-3-fluorobenzonitrile; 1-(4-Cyano-2-fluorophenyl)-4-chloro-1H-pyrazole; 4-(4-Chloropyrazol-1-yl)-3-fluorobenzonitrile; 3-Fluoro-4-(4-chloropyrazol-1-yl)benzonitrile
EINECS	Contact for details

Quality Control

Every batch of Benzonitrile, 4-(4-Chloro-1H-Pyrazol-1-Yl)-3-Fluoro- is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and process chemistry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, NMR, and MS is supplied with each shipment. Our quality protocols are designed to support regulatory filings in target industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.