Description

1-(4-Fluoro-2-Nitrophenyl)-4-Methyl-1H-Pyrazole is a high-purity fluorinated pyrazole derivative, serving as a critical building block in advanced organic synthesis. This compound is valued for its unique molecular architecture, which incorporates both a nitro and a fluoro substituent on the phenyl ring, making it an essential intermediate for creating complex, functionalized molecules. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly in kinase inhibitor and other small-molecule therapeutic programs.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the fluorinated pyrazole core contributes to biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for the synthesis of specialized ligands, dyes, and functional organic materials.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	1-(4-Fluoro-2-Nitrophenyl)-4-Methyl-1H-Pyrazole
CAS No.	1170905-81-3
Molecular Formula	C10H8FN3O2
Molecular Weight	221.19 g/mol
Synonyms	4-Methyl-1-(4-fluoro-2-nitrophenyl)-1H-pyrazole; 1-(4-Fluoro-2-nitrophenyl)-4-methylpyrazole; 4-Methyl-1-(4-fluoro-2-nitrophenyl)pyrazole; 1H-Pyrazole, 1-(4-fluoro-2-nitrophenyl)-4-methyl-; 1170905-81-3; 4-Methyl-1-(2-nitro-4-fluorophenyl)-1H-pyrazole
EINECS	Contact for details

Quality Control

Our 1-(4-Fluoro-2-Nitrophenyl)-4-Methyl-1H-Pyrazole is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices for research-grade intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This compound is light-sensitive and easily oxidized; for long-term storage, consider an inert atmosphere (e.g., nitrogen or argon) to maintain optimal stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.