Description

5-Chloro-1-Fluoro-2-Methyl-3-Nitrobenzene is a high-purity, multi-functional halogenated nitrobenzene derivative, serving as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it an indispensable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a halogenated aromatic core.
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and insecticides, where the nitro and halogen groups are essential for bioactivity.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers and liquid crystals.
• Dye and Pigment Manufacturing: Intermediate for producing complex azo dyes and other colorants requiring specific halogen and nitro substituents.
• Cross-Coupling Reactions: Valuable substrate in palladium-catalyzed reactions (e.g., Suzuki, Buchwald-Hartwig) for creating biaryl structures.
• Organic Synthesis Building Block: Versatile starting material for further functional group transformations in academic and industrial research laboratories.

Basic Information

Item	Details
Product Name	5-Chloro-1-Fluoro-2-Methyl-3-Nitrobenzene
CAS No.	1167056-41-8
Molecular Formula	C7H5ClFNO2
Molecular Weight	189.57 g/mol
Synonyms	1-Chloro-4-fluoro-5-methyl-2-nitrobenzene; 2-Methyl-5-chloro-1-fluoro-3-nitrobenzene; 3-Nitro-5-chloro-2-fluorotoluene; 5-Chloro-2-fluoro-3-nitrotoluene; 5-Chloro-2-fluoro-α-methyl-3-nitrobenzene; 5-Chloro-2-fluoro-3-nitro-1-methylbenzene; Benzene, 5-chloro-1-fluoro-2-methyl-3-nitro-
EINECS	Contact for details

Quality Control

Our 5-Chloro-1-Fluoro-2-Methyl-3-Nitrobenzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.