Description

3,5-Dibromo-2-Fluorobenzonitrile is a high-purity fluorinated aromatic nitrile building block, distinguished by its strategic halogen substitution pattern. This compound is critical for introducing specific steric and electronic properties into advanced molecular architectures, enabling precise tuning of material and biological activity. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for applications in drug discovery, ligand synthesis, and the development of functional polymers.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides and fungicides, where the fluorine and bromine atoms contribute to enhanced bioavailability and environmental stability.
• Ligand & Catalyst Development: Employed in organometallic chemistry to create specialized ligands for transition metal catalysts used in cross-coupling reactions.
• Material Science Research: Acts as a monomer or functionalization agent in the synthesis of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probe: Utilized in medicinal chemistry for structure-activity relationship (SAR) studies and as a building block for fluorescent tags or molecular probes.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes under cGMP or ISO 9001 frameworks.

Basic Information

Product Name	3,5-Dibromo-2-Fluorobenzonitrile
CAS No.	1160574-05-9
Molecular Formula	C7H2Br2FN
Molecular Weight	278.90 g/mol
Synonyms	2-Fluoro-3,5-dibromobenzonitrile; 3,5-Dibromo-2-fluorobenzonitrile; Benzonitrile, 3,5-dibromo-2-fluoro-; 2-Fluoro-3,5-dibromobenzene carbonitrile; 1160574-05-9; 3,5-Dibromo-2-fluorobenzene-1-carbonitrile; 2-Fluoro-3,5-dibromophenyl cyanide
EINECS	Contact for details

Quality Control

Our 3,5-Dibromo-2-Fluorobenzonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific project requirements, including research-grade or cGMP standards for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.