Description

2-Bromo-5-(Cyanomethyl)Benzotrifluoride is a high-value, multi-functional aromatic building block designed for advanced organic synthesis. This compound is engineered to provide a trifluoromethyl group, a bromine atom, and a cyanomethyl moiety in a single, strategically functionalized benzene ring, enabling efficient construction of complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of functional polymers, liquid crystals, and organic electronic materials due to its unique electronic properties imparted by the fluorine atoms.
• Chemical Biology Probes: Useful for synthesizing tagged molecules and probes for studying biological pathways and protein interactions.

Basic Information

Product Name	2-Bromo-5-(Cyanomethyl)Benzotrifluoride
CAS No.	1159512-69-2
Molecular Formula	C9H5BrF3N
Molecular Weight	264.04 g/mol
Synonyms	2-Bromo-5-(cyanomethyl)-α,α,α-trifluorotoluene; 1-Bromo-4-(cyanomethyl)-2-(trifluoromethyl)benzene; 2-Bromo-α,α,α-trifluoro-5-(cyanomethyl)toluene; 5-(Cyanomethyl)-2-bromobenzotrifluoride; [2-Bromo-5-(trifluoromethyl)phenyl]acetonitrile; Benzene, 1-bromo-4-(cyanomethyl)-2-(trifluoromethyl)-; (2-Bromo-5-(trifluoromethyl)phenyl)acetonitrile
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-(Cyanomethyl)Benzotrifluoride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed in a dry environment to minimize moisture exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.