Description

5-Fluoro-2-Isopropoxybenzonitrile is a high-purity, advanced pharmaceutical intermediate characterized by its distinct benzonitrile core substituted with fluorine and isopropoxy groups. This compound matters as a critical building block in modern organic synthesis, enabling the development of novel active pharmaceutical ingredients (APIs) with enhanced properties. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of complex molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS and oncology.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, leveraging the fluorine moiety for improved biological activity and metabolic stability.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for display technologies.
• Organic Light-Emitting Diodes (OLEDs): Acts as a building block for electron-transport or host materials in OLED device fabrication.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new reactions and creating compound libraries.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for clients.

Basic Information

Product Name	5-Fluoro-2-Isopropoxybenzonitrile
CAS No.	1158506-01-4
Molecular Formula	C10H10FNO
Molecular Weight	179.19 g/mol
Synonyms	2-Isopropoxy-5-fluorobenzonitrile; 5-Fluoro-2-(1-methylethoxy)benzonitrile; Benzonitrile, 5-fluoro-2-(1-methylethoxy)-; 5-Fluoro-2-isopropoxybenzonitrile; 1158506-01-4; 5-Fluoro-2-(propan-2-yloxy)benzonitrile
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2-Isopropoxybenzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.