Description

3-Fluoro-4-(Methylamino)Benzonitrile is a high-purity fluorinated aromatic nitrile building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its unique substitution pattern enables precise molecular modifications. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for creating novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, leveraging the fluorine atom for enhanced bioactivity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of advanced organic electronic materials and liquid crystals due to its electron-withdrawing nitrile group and fluorine atom.
• Chemical Biology Probes: Utilized as a scaffold for developing fluorescent tags and molecular probes for studying biological processes.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects requiring specific fluorinated aniline derivatives.

Basic Information

Item	Details
Product Name	3-Fluoro-4-(Methylamino)Benzonitrile
CAS No.	1157057-81-2
Molecular Formula	C8H7FN2
Molecular Weight	150.15 g/mol
Synonyms	4-(Methylamino)-3-fluorobenzonitrile; 3-Fluoro-4-methylaminobenzonitrile; 3-Fluoro-N-methyl-4-cyanobenzeneamine; 4-Cyano-2-fluoro-N-methylaniline; Benzonitrile, 3-fluoro-4-(methylamino)-; 1157057-81-2; FC-0812 (Potential internal code); 3-F-4-MABN (Abbreviation)
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4-(Methylamino)Benzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support compliance with ICH Q7 guidelines and can tailor quality protocols to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.