Description

4-Ethoxy-3-Fluorobenzonitrile is a high-purity fluorinated aromatic nitrile building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both an ethoxy and a fluorine substituent on the benzonitrile core, makes it a versatile intermediate for constructing complex molecules. This compound is primarily utilized by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other biologically active molecules.
• Agrochemical Synthesis: Serves as a crucial building block for creating novel herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Liquid Crystal & OLED Material Research: Used in the development of advanced electronic display materials and organic light-emitting diodes (OLEDs) due to its fluorinated aromatic structure.
• Functional Material Development: Employed in synthesizing specialty polymers, ligands for catalysis, and other performance chemicals requiring specific electronic properties.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D exploring new fluorination reactions and cross-coupling methodologies.

Basic Information

Product Name	4-Ethoxy-3-Fluorobenzonitrile
CAS No.	1156079-46-7
Molecular Formula	C9H8FNO
Molecular Weight	165.17 g/mol
Synonyms	3-Fluoro-4-ethoxybenzonitrile; 4-Ethoxy-3-fluorobenzene carbonitrile; Benzonitrile, 4-ethoxy-3-fluoro-; 3-Fluoro-4-ethoxybenzonitrile; 1156079-46-7
EINECS	Contact for details

Quality Control

Our 4-Ethoxy-3-Fluorobenzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports applications requiring high-purity intermediates for GLP and cGMP development work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be stored away from light as indicated.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.