Description

Hydroxy-(4-Trifluoromethoxy-Phenyl)-Acetonitrile is a versatile and high-value fluorinated organic intermediate. This compound is critical for the synthesis of advanced molecules, offering a trifluoromethoxy-substituted benzylic nitrile moiety that is highly sought after in modern chemical development. It is primarily needed by pharmaceutical, agrochemical, and advanced material research and development teams for constructing complex active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in CNS and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, where the trifluoromethoxy group enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated components in electronic display and lighting technologies.
• Advanced Polymer Modification: Incorporated to introduce specific functional groups into polymer backbones, altering physical and chemical properties.
• Organic Synthesis Reagent: Utilized in academic and industrial R&D for constructing complex molecular architectures via cyano and hydroxyl group transformations.

Basic Information

Product Name	Hydroxy-(4-Trifluoromethoxy-Phenyl)-Acetonitrile
CAS No.	1155915-20-0
Molecular Formula	C9H6F3NO2
Molecular Weight	217.14 g/mol
Synonyms	4-(Trifluoromethoxy)mandelonitrile; (4-Trifluoromethoxyphenyl)(hydroxy)acetonitrile; α-Hydroxy-4-(trifluoromethoxy)benzeneacetonitrile; 2-Hydroxy-2-[4-(trifluoromethoxy)phenyl]acetonitrile; 4-Trifluoromethoxy Mandelonitrile; p-Trifluoromethoxy Mandelonitrile; 1155915-20-0
EINECS	Contact for details

Quality Control

Our Hydroxy-(4-Trifluoromethoxy-Phenyl)-Acetonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.