Description

n-(2-Cyano-3-Fluorophenyl)Acetamide is a high-purity fluorinated aromatic acetamide derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both cyano and fluoro substituents, makes it a versatile intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in developing new herbicides, fungicides, and insecticides where the fluorinated aromatic core enhances biological activity and metabolic stability.
• Material Science: Building block for advanced polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing groups.
• Chemical Synthesis: Serves as a versatile reagent for palladium-catalyzed cross-coupling reactions, such as Suzuki or Buchwald-Hartwig amination.
• Fluorine Chemistry Studies: Valuable substrate for investigating the influence of fluorine atoms on reaction pathways and molecular properties in academic and industrial R&D.

Basic Information

Product Name	n-(2-Cyano-3-Fluorophenyl)Acetamide
CAS No.	1155146-72-7
Molecular Formula	C9H7FN2O
Molecular Weight	178.16 g/mol
Synonyms	2-Acetamido-6-fluorobenzonitrile; N-(2-Cyano-3-fluorophenyl)acetamide; 2-Fluoro-6-cyanophenylacetamide; Acetamide, N-(2-cyano-3-fluorophenyl)-; 3-Fluoro-2-cyanophenylacetamide; 1155146-72-7; 2-Cyano-3-fluoroacetamilide
EINECS	Contact for details

Quality Control

Our n-(2-Cyano-3-Fluorophenyl)Acetamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding research and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.