Description

4-Bromo-3-(trifluoromethyl)pyridine is a versatile halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both bromine and a trifluoromethyl group on the pyridine ring, makes it a highly valuable intermediate for introducing these functional motifs into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing properties of the trifluoromethyl group.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science: Employed in the synthesis of functional polymers, liquid crystals, and electronic materials that require halogenated or fluorinated aromatic components.
• Chemical Research & Development: A valuable reagent for medicinal chemistry, process chemistry, and exploring new synthetic methodologies in academic and industrial R&D labs.

Basic Information

Item	Details
Product Name	4-Bromo-3-(trifluoromethyl)pyridine
CAS No.	1138011-21-8
Molecular Formula	C6H3BrF3N
Molecular Weight	225.99 g/mol
Synonyms	3-(Trifluoromethyl)-4-bromopyridine; 4-Bromo-3-trifluoromethylpyridine; 4-Bromo-α,α,α-trifluoro-3-picoline; Pyridine, 4-bromo-3-(trifluoromethyl)-; 4-Bromo-3-(trifluoromethyl)pyridine; 4-Bromo-3-(trifluoromethyl)pyridine (CAS 1138011-21-8)
EINECS	Contact for details

Quality Control

Our 4-Bromo-3-(trifluoromethyl)pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistent quality suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed specifications are provided for each shipment, ensuring full traceability and compliance with customer requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (HPLC/GC-MS)	Conforms to reference standard
Purity (HPLC)	≥ 97.0% (Standard Grade)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.