Description

Amino-(3-Fluoro-Phenyl)-Acetic Acid Hcl is a high-purity fluorinated phenylglycine derivative, a crucial chiral building block in modern synthetic chemistry. Its value lies in its role as a key intermediate for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs). This compound is essential for research and production teams in the pharmaceutical, agrochemical, and advanced material science industries seeking to incorporate a fluorinated aromatic amino acid motif.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel drug candidates, especially in protease inhibitors and receptor antagonists.
• Agrochemical Research: Used in developing advanced herbicides and pesticides where the fluorine atom enhances biological activity and stability.
• Peptide Synthesis: Serves as a protected amino acid derivative for the solid-phase or solution-phase synthesis of fluorinated peptides.
• Ligand & Catalyst Development: Employed in creating specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the design of molecular probes and biomarkers for studying biological pathways.
• Material Science: A precursor for specialty polymers and advanced organic materials requiring fluorinated aromatic components.

Basic Information

Product Name	Amino-(3-Fluoro-Phenyl)-Acetic Acid Hcl
CAS No.	1137474-81-7
Molecular Formula	C8H9FNO2 • HCl
Molecular Weight	203.62 (Free base) / 240.08 (HCl salt)
Synonyms	(3-Fluorophenyl)glycine hydrochloride; 2-Amino-2-(3-fluorophenyl)acetic acid hydrochloride; 3-Fluoro-DL-phenylglycine HCl; DL-3-Fluorophenylglycine hydrochloride; α-Amino-(3-fluorophenyl)acetic acid HCl; Amino(3-fluorophenyl)ethanoic acid hydrochloride; m-Fluorophenylglycine hydrochloride
EINECS	Contact for details

Quality Control

Our Amino-(3-Fluoro-Phenyl)-Acetic Acid Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and residual solvent screening, to ensure it meets the stringent requirements for advanced synthetic applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.