Description

2-Chloro-6-(Dibromomethyl)-3-Fluorobenzonitrile is a high-purity, multi-functional halogenated aromatic nitrile building block. This compound matters for its unique molecular architecture, which combines chloro, fluoro, and dibromomethyl substituents on a benzonitrile core, making it a versatile intermediate for advanced synthesis. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecules, particularly in the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, especially in medicinal chemistry programs targeting CNS disorders and anti-infectives.
• Agrochemical Active Ingredient Precursor: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging its halogenated structure.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of advanced polymers and liquid crystals where halogenated aromatic units are required for specific electronic or physical properties.
• Custom Synthesis and Contract Manufacturing: Supplied to CROs and CDMOs for use in client-specific projects requiring complex halogenated intermediates.

Basic Information

Product Name	2-Chloro-6-(Dibromomethyl)-3-Fluorobenzonitrile
CAS No.	1134335-07-1
Molecular Formula	C8H3Br2ClFN
Molecular Weight	327.37 g/mol
Synonyms	3-Fluoro-2-chloro-6-(dibromomethyl)benzonitrile; 2-Chloro-3-fluoro-6-(dibromomethyl)benzonitrile; 6-(Dibromomethyl)-2-chloro-3-fluorobenzonitrile; Benzonitrile, 2-chloro-6-(dibromomethyl)-3-fluoro-; 1134335-07-1; Halogenated Benzonitrile Intermediate; Dibromomethyl Chloro Fluoro Benzonitrile
EINECS	Contact for details

Quality Control

Our 2-Chloro-6-(Dibromomethyl)-3-Fluorobenzonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We support cGMP compliance for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque or amber packaging, or stored in darkness.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.