Description

5-Bromo-2,3-Difluorobenzonitrile is a high-purity, multi-functional aromatic building block essential for advanced organic synthesis. Its unique halogenated and nitrile-substituted structure makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the development of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, leveraging the difluoro and bromo substituents for bioactivity.
• Liquid Crystal & OLED Material Precursor: Serves as a foundational unit for synthesizing fluorinated aromatic cores used in electronic display technologies and organic light-emitting diodes.
• Polymer & Material Science: Incorporated into specialty polymers and high-performance resins to enhance thermal stability, chemical resistance, and specific functional properties.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions, enabling rapid diversification of molecular scaffolds in medicinal chemistry.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D exploring new reaction methodologies and heterocyclic compound libraries.

Basic Information

Product Name	5-Bromo-2,3-Difluorobenzonitrile
CAS No.	1105665-42-6
Molecular Formula	C7H2BrF2N
Molecular Weight	218.00 g/mol
Synonyms	2,3-Difluoro-5-bromobenzonitrile; 5-Bromo-2,3-difluorobenzene carbonitrile; Benzonitrile, 5-bromo-2,3-difluoro-; 2,3-Difluoro-5-bromophenyl cyanide; 1105665-42-6; 5-Br-2,3-F2-C6H2-CN
EINECS	Contact for details

Quality Control

Our 5-Bromo-2,3-Difluorobenzonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.