Description

4-Amino-2-Chloro-6-Fluorobenzonitrile is a high-purity, multi-functional aromatic nitrile building block. This compound is valued for its unique substitution pattern, which makes it a critical intermediate in the synthesis of complex organic molecules. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing novel drug candidates, particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging its halogenated aniline structure.
• Material Science Research: Serves as a precursor for functional dyes, liquid crystals, and advanced polymers due to its electron-withdrawing nitrile and electron-donating amino groups.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Buchwald-Hartwig amination, Suzuki coupling) to create complex, multi-substituted aromatic systems for various R&D applications.

Basic Information

Product Name	4-Amino-2-Chloro-6-Fluorobenzonitrile
CAS No.	1095188-13-8
Molecular Formula	C7H4ClFN2
Molecular Weight	170.57 g/mol
Synonyms	2-Chloro-6-fluoro-4-aminobenzonitrile; 4-Amino-2-chloro-6-fluorobenzene carbonitrile; 2-Chloro-4-cyano-3-fluoroaniline; 3-Fluoro-5-amino-6-chlorobenzonitrile; Benzonitrile, 4-amino-2-chloro-6-fluoro-; 6-Fluoro-2-chloro-1,4-benzenediamine-3-carbonitrile
EINECS	Contact for details

Quality Control

Our 4-Amino-2-Chloro-6-Fluorobenzonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all specifications are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.