Description

2,5-Difluoro-1-Methyl-3-Nitrobenzene is a high-purity fluorinated nitroaromatic compound, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic placement of fluorine and nitro substituents on the benzene ring, which enables precise molecular modifications essential for developing novel compounds. This intermediate is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in fluorine-containing drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, pesticides, and fungicides where the difluoro-methylnitrobenzene scaffold imparts specific biological activity.
• Material Science Research: Serves as a precursor for synthesizing specialty polymers, liquid crystals, and electronic materials that benefit from fluorinated aromatic structures.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, nucleophilic aromatic substitutions, and reduction reactions to create complex, multi-functional molecules.
• Dye and Pigment Intermediate: Utilized in the synthesis of specialized fluorinated dyes and pigments for high-performance applications.

Basic Information

Product Name	2,5-Difluoro-1-Methyl-3-Nitrobenzene
CAS No.	1093758-82-7
Molecular Formula	C7H5F2NO2
Molecular Weight	173.12 g/mol
Synonyms	1,4-Difluoro-2-methyl-5-nitrobenzene; 2-Methyl-3,6-difluoronitrobenzene; 3-Nitro-2,5-difluorotoluene; 2,5-Difluoro-3-nitrotoluene; 2,5-Difluoro-1-methyl-3-nitro-benzene; 2,5-Difluoro-3-nitrotoluene; 2-Methyl-1,4-difluoro-5-nitrobenzene
EINECS	Contact for details

Quality Control

Every batch of 2,5-Difluoro-1-Methyl-3-Nitrobenzene is produced and tested under a strict quality management system. We ensure compliance with relevant industry standards for fine chemical intermediates. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee consistent quality and reliable performance in your synthetic processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.