Description

4-Hydroxy-3-(Trifluoromethoxy)Benzonitrile is a versatile fluorinated aromatic nitrile building block. Its molecular structure, featuring both a phenolic hydroxyl group and a trifluoromethoxy substituent, makes it a critical intermediate for synthesizing advanced materials and active pharmaceutical ingredients (APIs). This compound is essential for R&D and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate unique fluorine-based properties into their final products.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, where the trifluoromethoxy group enhances biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor for fluorinated liquid crystal compounds used in high-performance displays.
• Polymer Chemistry: An intermediate for creating specialty polymers with enhanced thermal stability and chemical resistance.
• Organic Synthesis: A versatile reagent for constructing complex aromatic systems in academic and industrial research laboratories.
• Material Science: Used in the development of organic electronic materials and advanced coatings.

Basic Information

Product Name	4-Hydroxy-3-(Trifluoromethoxy)Benzonitrile
CAS No.	1093397-72-8
Molecular Formula	C8H4F3NO2
Molecular Weight	203.12 g/mol
Synonyms	3-(Trifluoromethoxy)-4-hydroxybenzonitrile; 4-Cyano-2-(trifluoromethoxy)phenol; 2-Hydroxy-5-(trifluoromethoxy)benzonitrile; 4-Hydroxy-3-trifluoromethoxybenzonitrile; Phenol, 4-cyano-2-(trifluoromethoxy)-; 1093397-72-8; 4-Hydroxy-α,α,α-trifluoro-m-toluonitrile
EINECS	Contact for details

Quality Control

Our 4-Hydroxy-3-(Trifluoromethoxy)Benzonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.