Description

4-Fluoro-1-Isopropoxy-2-Nitrobenzene is a specialized aromatic nitro compound featuring both fluoro and isopropoxy substituents, making it a valuable intermediate in advanced organic synthesis. Its molecular structure is engineered to facilitate selective chemical transformations, particularly in the construction of complex heterocyclic systems and active pharmaceutical ingredients (APIs). This high-purity intermediate is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable building blocks for innovative molecule design.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those containing fluorinated aromatic or heterocyclic moieties.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides where the fluorine atom enhances biological activity and stability.
• Liquid Crystal & OLED Material Research: Serves as a precursor for developing fluorinated organic electronic materials due to its specific substitution pattern.
• Dye & Pigment Intermediate: Employed in the synthesis of specialized nitro- and fluoro-containing dyes and colorants.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed reactions (e.g., Suzuki, Buchwald-Hartwig) for creating biaryl structures.
• Academic & Contract Research: A valuable reagent for methodological development and exploratory chemistry in university and CRO laboratories.

Basic Information

Product Name	4-Fluoro-1-Isopropoxy-2-Nitrobenzene
CAS No.	1092496-27-9
Molecular Formula	C9H10FNO3
Molecular Weight	199.18 g/mol
Synonyms	1-Fluoro-4-isopropoxy-2-nitrobenzene; 2-Nitro-4-fluorophenyl isopropyl ether; 4-Fluoro-2-nitro-1-isopropoxybenzene; 4-Fluoro-2-nitrophenyl isopropyl ether; Isopropyl 4-fluoro-2-nitrophenyl ether; Benzene, 1-fluoro-4-(1-methylethoxy)-2-nitro-; (4-Fluoro-2-nitrophenoxy)propane
EINECS	Contact for details

Quality Control

Our 4-Fluoro-1-Isopropoxy-2-Nitrobenzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, GC for residual solvents, and NMR/IR for structural confirmation, to ensure it meets the high standards required for synthetic applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.