Description

3-Chloro-4-(Trifluoromethyl)Benzonitrile is a high-value, multi-functional aromatic nitrile building block distinguished by its chloro and trifluoromethyl substituents. This compound is engineered to serve as a critical intermediate in advanced organic synthesis, where its unique halogenated and fluorinated structure enables the development of novel molecules with tailored properties. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting new therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing properties of the trifluoromethyl group.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the creation of monomers and functionalized polymers for advanced materials with specific electronic or surface properties.
• Fluorine Chemistry Building Block: Essential for introducing the trifluoromethyl moiety into complex molecular architectures in discovery chemistry.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	3-Chloro-4-(Trifluoromethyl)Benzonitrile
CAS No.	1092460-79-1
Molecular Formula	C8H3ClF3N
Molecular Weight	205.56 g/mol
Synonyms	3-Chloro-4-(trifluoromethyl)benzonitrile; 4-Cyano-2-chlorobenzotrifluoride; 2-Chloro-α,α,α-trifluoro-p-tolunitrile; 2-Chloro-4-cyanobenzotrifluoride; Benzonitrile, 3-chloro-4-(trifluoromethyl)-; 3-Chloro-4-trifluoromethylbenzonitrile; p-Cyanobenzotrifluoride, 2-chloro-
EINECS	Contact for details

Quality Control

Our 3-Chloro-4-(Trifluoromethyl)Benzonitrile is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for research and industrial synthesis. Certificates of Analysis (COA) with full chromatographic and spectroscopic data are provided to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.