Description

3-Ethoxy-2,6-Difluorobenzonitrile is a high-purity fluorinated aromatic nitrile building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both ethoxy and fluorine substituents, makes it a versatile intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for constructing heterocyclic cores and fluorinated bioactive molecules.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides where the difluoro and nitrile groups contribute to biological activity and metabolic stability.
• Liquid Crystal & OLED Material Research: Serves as a precursor for fluorinated aromatic compounds used in electronic materials, leveraging its ability to modify polarity and intermolecular interactions.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution to introduce the 2,6-difluoro-3-ethoxybenzonitrile moiety into more complex structures.
• Chemical Research & Development: Essential for academic and industrial labs exploring new synthetic methodologies and the properties of fluorinated aromatic systems.

Basic Information

Product Name	3-Ethoxy-2,6-Difluorobenzonitrile
CAS No.	1092460-60-0
Molecular Formula	C9H7F2NO
Molecular Weight	183.16 g/mol
Synonyms	2,6-Difluoro-3-ethoxybenzonitrile; 3-Ethoxy-2,6-difluorobenzonitrile; Benzonitrile, 3-ethoxy-2,6-difluoro-; 1092460-60-0
EINECS	Contact for details

Quality Control

Our 3-Ethoxy-2,6-Difluorobenzonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, confirming compliance with customer specifications and industry best practices.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.