Description

2-Ethyl-4-Fluoro-1-Nitrobenzene is a specialized fluorinated nitroaromatic compound serving as a crucial building block in advanced organic synthesis. Its value lies in the strategic placement of functional groups, enabling precise chemical modifications for creating complex molecular architectures. This intermediate is primarily needed by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a fluorinated aromatic core for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atom and nitro group are critical for biological activity.
• Material Science Research: Employed in the development of specialty polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing nitro and fluorine substituents.
• Dye and Pigment Intermediate: Acts as a starting material for synthesizing complex fluorinated dyes and pigments with unique color fastness and spectral properties.
• Cross-Coupling Reactions: Serves as a substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to construct biaryl systems, a common motif in medicinal chemistry.

Basic Information

Item	Detail
Product Name	2-Ethyl-4-Fluoro-1-Nitrobenzene
CAS No.	1089279-29-7
Molecular Formula	C8H8FNO2
Molecular Weight	169.15 g/mol
Synonyms	1-Ethyl-2-fluoro-5-nitrobenzene; 4-Fluoro-2-ethylnitrobenzene; 2-Ethyl-4-fluoronitrobenzene; 2-Fluoro-5-nitroethylbenzene; 5-Nitro-2-fluoroethylbenzene; 1089279-29-7; 2-Ethyl-4-fluoro-1-nitro-benzene
EINECS	Contact for details

Quality Control

Our 2-Ethyl-4-Fluoro-1-Nitrobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.