Description

5-Fluoro-2-Methyl-3-Nitrobenzonitrile is a high-purity, multi-functional aromatic nitrile building block designed for advanced synthetic chemistry. This compound is valued for its unique trifunctional molecular scaffold, which enables the efficient synthesis of complex heterocycles and active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for developing novel compounds and fine-tuning molecular properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides and pesticides, leveraging the fluorine atom for enhanced bioactivity and environmental stability.
• Material Science Research: Serves as a building block for creating specialty polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing nitro and nitrile groups.
• Chemical Biology & Proteomics: Employed as a versatile scaffold for designing activity-based probes and molecular tags for protein labeling and imaging studies.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring the introduction of fluorine, methyl, nitro, and nitrile functionalities in a single step.

Basic Information

Product Name	5-Fluoro-2-Methyl-3-Nitrobenzonitrile
CAS No.	1082040-41-2
Molecular Formula	C8H5FN2O2
Molecular Weight	180.14 g/mol
Synonyms	3-Nitro-5-fluoro-2-methylbenzonitrile; 2-Methyl-3-nitro-5-fluorobenzonitrile; Benzonitrile, 5-fluoro-2-methyl-3-nitro-; 5-Fluoro-2-methyl-3-nitrobenzenecarbonitrile; 1082040-41-2
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2-Methyl-3-Nitrobenzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and away from direct light sources to maintain stability and prevent degradation. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.