Description

8-Trifluoromethyl-Quinolin-6-Ylamine is a high-value, multi-functional quinoline derivative characterized by its trifluoromethyl and amine functional groups. This compound serves as a critical advanced pharmaceutical intermediate and organic synthesis building block, enabling the development of novel active ingredients. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science sectors for the synthesis of complex molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders, oncology, and anti-infectives.
• Agrochemical Research: Building block for developing new generation herbicides, fungicides, and insecticides, leveraging the biological activity of the quinoline scaffold.
• Organic Light-Emitting Diodes (OLEDs): Used in the research and development of electron-transport or host materials for optoelectronic devices.
• Ligand Synthesis: Serves as a starting material for creating novel ligands in catalytic and coordination chemistry.
• Fluorescent Probe Development: Utilized in the design of molecular probes and sensors for biochemical detection and imaging.
• Material Science: Intermediate for synthesizing specialty polymers and advanced functional materials with unique properties.

Basic Information

Product Name	8-Trifluoromethyl-Quinolin-6-Ylamine
CAS No.	1080640-91-0
Molecular Formula	C10H7F3N2
Molecular Weight	212.17 g/mol
Synonyms	6-Amino-8-(trifluoromethyl)quinoline; 8-(Trifluoromethyl)quinolin-6-amine; 8-Trifluoromethyl-6-quinolinamine; Quinoline, 6-amino-8-(trifluoromethyl)-; 1080640-91-0; 8-Trifluoromethylquinolin-6-ylamine
EINECS	Contact for details

Quality Control

Our 8-Trifluoromethyl-Quinolin-6-Ylamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.